Antipsychotic Treatment Resistance in Schizophrenia Associated with Elevated Glutamate Levels but Normal Dopamine Function

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Bibliographic Details
Published in:Biological psychiatry (1969) 2014-03, Vol.75 (5), p.e11-e13
Main Authors: Demjaha, Arsime, Egerton, Alice, Murray, Robin M, Kapur, Shitij, Howes, Oliver D, Stone, James M, McGuire, Philip K
Format: Article
Language:English
Subjects:
Analysis of Variance
Antipsychotic Agents - therapeutic use
Aspartic Acid - analogs & derivatives
Aspartic Acid - metabolism
Dihydroxyphenylalanine - analogs & derivatives
Dihydroxyphenylalanine - pharmacokinetics
Dopamine - metabolism
Female
Glutamic Acid - metabolism
Humans
Magnetic Resonance Spectroscopy
Male
Positron-Emission Tomography
Protons
Psychiatry
Schizophrenia - diagnostic imaging
Schizophrenia - drug therapy
Schizophrenia - metabolism
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ISSN:0006-3223
1873-2402
DOI:10.1016/j.biopsych.2013.06.011