Chemical constituents from the heartwood of Toxicodendron vernicifluum (Stokes) F.A. Barkley

• Published in: Biochemical systematics and ecology 2020-06, Vol.90, p.104017, Article 104017
• Main Authors: Li, Mei Chen, Xie, Chao Jie, Gao, Jin Gou, Meng, Cai Wen, He, Yuan Jiang, Liu, Jian Yu, Xu, Yong Nan
• Format: Article
• Language: English
• Subjects: Benzoic acid derivative; Flavonoid; Sterol; Toxicodendron vernicifluum; Triterpene
• ISSN: 0305-1978; 1873-2925
• DOI: 10.1016/j.bse.2020.104017

A phytochemical investigation of the heartwood of Toxicodendron vernicifluum (Stokes) F.A. Barkley led to the isolation of twenty-five compounds, including sixteen flavonoids (1–15), one flavonolignan (16), one chromone (17), four benzoic acid derivatives (18–21), two triterpenes (22–23) and two sterols (24–25). The structures of these compounds were elucidated on the basis of spectroscopic analysis and comparison with previous literature data. Among them, 8 and 21were isolated from the genus Toxicodendron and 5, 9, 13, 17–20, 22 from the family Anacardiaceae for the first time. Furthermore, 21 had been identified only by LC/MS before. 20 was a synthetic product used as anthelmintics, newly identified as a natural product. Furthermore, the chemotaxonomic value of these isolates was also discussed in detail. [Display omitted] •5, 9, 13, 17–20, 22 were isolated from the family Anacardiaceae for the first time.•8 and 21were isolated from the genus Toxicodendron for the first time.•NMR data of one compound which was first reported from natural source was reported.•The chemotaxonomic significance of the isolated compounds is discussed.