Chemical constituents of Euphorbia lathyris and their chemotaxonomic significance

A comprehensive analysis of the chemical constituents of the traditional Chinese herb Euphorbia lathyris yielded the isolation and characterization of a novel lathyrane diterpene (1), six previously identified lathyrane diterpenes (2−7), two triterpenes (8−9), three sterols (10−12), and one sesquite...

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Bibliographic Details
Published in:Biochemical systematics and ecology 2025-06, Vol.120, p.104952, Article 104952
Main Authors: Yuan, Changchun, Liang, Yun, Xun, Miao-Miao, Li, Yuqiang, Ji, Haixia, Fu, Kai
Format: Article
Language:English
Subjects:
Chemotaxonomic significance
Euphorbia
Euphorbia lathyris
Lathyrane diterpene
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Summary:A comprehensive analysis of the chemical constituents of the traditional Chinese herb Euphorbia lathyris yielded the isolation and characterization of a novel lathyrane diterpene (1), six previously identified lathyrane diterpenes (2−7), two triterpenes (8−9), three sterols (10−12), and one sesquiterpene (13). The molecular structures of these constituents were elucidated through the application of an extensive array of spectroscopic methods, and the absolute configuration of the new diterpene 1 was ascertained using time-dependent density functional theory (TDDFT) calculations. Notably, compounds 1−4 and 11−12 are being reported for the first time within the Euphorbia genus. Furthermore, the study also delves into the chemotaxonomic implications of these newly isolated compounds. •Thirteen compounds were isolated from the Euphorbia lathyrism, including a new one.•Compounds 1−4 and 11−12 are reported for the first time within the Euphorbia genus.•The chemotaxonomic significance of the isolates is discussed.
ISSN:0305-1978
DOI:10.1016/j.bse.2025.104952