Effect of single dose intravenous tranexamic acid on blood loss in tangential excision of burn wounds — A double blind randomised controlled trial

•Tangential excision of burns is associated with significant blood loss during surgery.•Tranexamic acid has proven to decrease blood loss in emergency and elective surgery.•Tranexamic acid use reduced blood loss per square centimeter of tangential excision in burns

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Bibliographic Details
Published in:Burns 2022-09, Vol.48 (6), p.1311-1318
Main Authors: K.S., Ajai, Kumar, Parmod, Subair, Mohsina, Sharma, Ramesh Kumar
Format: Article
Language:English
Subjects:
Antifibrinolytic Agents - therapeutic use
Blood loss
Blood Loss, Surgical - prevention & control
Blood transfusion
Burns - complications
Burns - drug therapy
Burns - surgery
Double-Blind Method
Gross formula
Hemoglobins
Humans
Prospective Studies
Tangential excision
Tranexamic acid
Tranexamic Acid - therapeutic use
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Description
Summary:•Tangential excision of burns is associated with significant blood loss during surgery.•Tranexamic acid has proven to decrease blood loss in emergency and elective surgery.•Tranexamic acid use reduced blood loss per square centimeter of tangential excision in burns
ISSN:0305-4179
1879-1409
DOI:10.1016/j.burns.2021.08.021