Progressive Worsening in Device-Based Heart Failure Sensor Measurements are Associated with Sub-Optimal LV Pacing Percentages in CRT-D Patients

• Published in: Journal of cardiac failure 2019-08, Vol.25 (8), p.S17-S17
• Main Authors: Boehmer, John P., Schloss, Edward J., Cao, Michael, Ahmed, Rezwan, Stolen, Craig, Varma, Niraj
• Format: Article
• Language: English
• ISSN: 1071-9164; 1532-8414
• DOI: 10.1016/j.cardfail.2019.07.051

Lower %LV pacing (35000 remotely monitored CRT patients. HeartLogic (HL), a heart failure (HF) composite index and alert algorithm available in both CRT-D and ICD devices, aggregates physiologic trends associated with multiple aspects of HF status (e.g. heart sounds, heart rate, thoracic impedance, respiration rate, tidal volume, and activity). HL alerts were recently shown to detect HF events with 70% sensitivity, and identify patients with 10-fold increased risk of worsening HF. We plan to investigate association between daily % LV pacing and device measured individual heart failure sensors and HeartLogic. The ALTITUDE database collects de-identified data recorded by the implanted devices from the LATITUDE remote monitoring system. Patients with HeartLogic enabled CRT-D devices and a minimum of 30 days of daily sensor data were included. All days with AF burden were excluded. Each patient day was grouped into 6 groups based on the daily % LV pacing values (