The influence of zinc chloride and zinc oxide nanoparticles on air-time survival in freshwater mussels

The purpose of this study was to determine the cumulative effects of exposure to either dissolved zinc or nanozinc oxide (nanoZnO) and air-time survival in freshwater mussels. Mussels were exposed to each forms of zinc for 96h then placed in air to determine survival time. A sub-group of mussels bef...

Full description

Saved in:
Bibliographic Details
Published in:Comparative biochemistry and physiology. Toxicology & pharmacology 2015-06, Vol.172-173, p.36-44
Main Authors: Gagné, François, Auclair, Joëlle, Peyrot, Caroline, Wilkinson, Kevin J.
Format: Article
Language:English
Subjects:
Air-time survival
Animals
Biomarkers
Bivalvia - physiology
Chlorides - chemistry
Chlorides - toxicity
Dose-Response Relationship, Drug
Elliptio complanata
inflammation
Inflammation - metabolism
Lipid Peroxidation
Metal Nanoparticles - chemistry
Metal Nanoparticles - toxicity
Oxidative Stress
Survival
Zinc Compounds - chemistry
Zinc Compounds - toxicity
Zinc Oxide - chemistry
Zinc Oxide - toxicity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose of this study was to determine the cumulative effects of exposure to either dissolved zinc or nanozinc oxide (nanoZnO) and air-time survival in freshwater mussels. Mussels were exposed to each forms of zinc for 96h then placed in air to determine survival time. A sub-group of mussels before and after 7days of exposure to air were kept aside for the determination of the following biomarkers: arachidonate-dependent cyclooxygenase (COX) and peroxidase (inflammation and oxidative stress), lipid metabolism (total lipids, esterases activity, HO-glycerol, acetyl CoA and phospholipase A2) and lipid damage (lipid peroxidation [LPO]). The results showed that air-time survival was decreased from a mean value of 18.5days to a mean value of 12days in mussels exposed to 2.5mg/L of nanoZnO although it was not lethal based on shell opening at concentrations below 50mg/L after 96h. In mussels exposed to zinc only, the median lethal concentration was estimated at 16mg/L (10–25 95% CI). The air-time survival did not significantly change in mussels exposed to the same concentration of dissolved Zn. Significant weight losses were observed at 0.5mg/L of nanoZnO and at 2.5mg/L for dissolved zinc chloride, and were also significantly correlated with air-time survival (r=0.53; p
ISSN:1532-0456
1878-1659
DOI:10.1016/j.cbpc.2015.04.005