Surface modification of MCM-41 and its application in DNA adsorption

Three types of MCM-41 absorbents, namely, Al~（3＋）-MCM-41, La~（3＋）-MCM-41, and Zn~（2＋）-MCM-41, were prepared through amine grafting, phosphonate modification, and metal ion chelation and characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, and N2adsorption-desorption...

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Bibliographic Details
Published in:Chinese chemical letters 2016, Vol.27 (1), p.139-144
Main Authors: Sun, Xiu-Yu, Li, Peng-Zhang, Ai, Bing, Wang, Yue-Bo
Format: Article
Language:English
Subjects:
Adsorption
DNA
DNA分子
MCM-41
NaCl溶液
Surface modification
介孔分子筛MCM-41
傅里叶变换红外光谱
吸附行为
应用
硬软酸碱原理
表面改性
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Summary:Three types of MCM-41 absorbents, namely, Al~（3＋）-MCM-41, La~（3＋）-MCM-41, and Zn~（2＋）-MCM-41, were prepared through amine grafting, phosphonate modification, and metal ion chelation and characterized by Fourier transform infrared spectroscopy, thermogravimetric analysis, and N2adsorption-desorption analysis. Results revealed that functionalized MCM-41 maintains the original structure of the molecular sieve and that the pore diameter and surface area are reduced compared with those of pure MCM-41. The adsorption behavior of DNA molecules on the surface of the modified molecular sieves was discussed according to the hard-soft acid-base（HSAB） principle. Experimental results showed that DNA purification could be effectively carried out on functionalized MCM-41 and that DNA is easily released by3-4 molL~（-1）NaCl solution. This study could be used as a general platform for future work on DNA adsorption and enrichment.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2015.08.008