Transformation of aldehydes or alcohols to amides at room temperature under aqueous conditions

A novel and efficient method for the synthesis of amide has been developed. The reactions proceeded smoothly under aqueous conditions at room temperature and generated the corresponding products in good to excellent yields. It is worth noting that alkyl amines which did not react in known approaches...

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Bibliographic Details
Published in:Chinese chemical letters 2017-07, Vol.28 (7), p.1597-1599
Main Authors: Dong, Dao-Qing, Hao, Shuang-Hong, Zhang, Hui, Wang, Zu-Li
Format: Article
Language:English
Subjects:
Aldehyde
Amides
Amine
Aqueous
合成方法
室温条件
水相
耐受性
转化
酰胺
醇
醛
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Summary:A novel and efficient method for the synthesis of amide has been developed. The reactions proceeded smoothly under aqueous conditions at room temperature and generated the corresponding products in good to excellent yields. It is worth noting that alkyl amines which did not react in known approaches are well tolerated in our system.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2017.03.008