Dual-site fluorescent probe for highly selective and sensitive detection of sulfite and biothiols

[Display omitted] A dual-site fluorescent probe that could discriminatively respond to Cys and HSO3− through two emission channels was reported, and it could further applied in imaging biothiols in living cells. A dual-site fluorescent probe with double bond and aldehyde as reactive sites, was desig...

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Bibliographic Details
Published in:Chinese chemical letters 2018-06, Vol.29 (6), p.992-994
Main Authors: Li, Mengyang, Cui, Pengcheng, Li, Kun, Feng, Jiahui, Zou, Mingming, Yu, Xiaoqi
Format: Article
Language:English
Subjects:
Biothiols
Cell imaging
Dual-site
Fluorescent probe
Sulfite
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Summary:[Display omitted] A dual-site fluorescent probe that could discriminatively respond to Cys and HSO3− through two emission channels was reported, and it could further applied in imaging biothiols in living cells. A dual-site fluorescent probe with double bond and aldehyde as reactive sites, was designed for the selective detection of sulfite and biothiols. Sulfite reacts with conjugate bond selectively, while Cys responses with aldehyde and GSH occurs substitution reaction. Different interactions cause different absorption and fluorescence responses. Moreover, it could be further applied in imaging in living cells.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2017.11.011