Fluorescent phenylthiazoles: Application as latent fingermark and their cytotoxicity against NOK-SI cell line

• Published in: Chemical Data Collections 2021-06, Vol.33, p.100700, Article 100700
• Main Authors: da Rosa, Bruno Nunes, Mariotti, Kristiane de Cássia, Pacheco, Bruna Silveira, da Silva, Caroline Carapina, Carreño, Neftalí Lenin Villarreal, Nicolodi, Caroline, Poletti, Tais, Silva, Allison Carlos Assunção, da Silva, Adriana Fernandes, Giongo, Janice Luehring, Vaucher, Rodrigo de Almeida, de Oliveira, Tiago Franco, de Pereira, Claudio Martin Pereira
• Format: Article
• Language: English
• Subjects: Cytotoxicity; Development powder; Fingermark; Forensic chemistry; Thiazoles
• ISSN: 2405-8300; 2405-8300
• DOI: 10.1016/j.cdc.2021.100700

Fingerprints are unique to each individual who contributes to human identification in forensic cases. In this sense, the present work aimed to synthesize 1H-pyrazol-1-yl-4-phenylthiazoles and apply them as powder agents to reveal latent finger marks as an alternative and low cost related to powders found on the market. The compounds were characterized by infrared; fluorescence; 1H NMR; 13C NMR; laser diffractometer and SEM. In addition, cytotoxicity was also evaluated in oral keratinocytes showing high cell viability. The result of the hemolytic assay revealed that compound 2a does not present red cell cytotoxicity. The prepared powders were applied to fingermarks deposited on different surfaces providing quality visualization at level three so that human identification is possible. [Display omitted]