Anti-inflammatory and anti-diabetic activity of 8-Hydroxyquinolinium 3,5-Dinitrobenzoate

An organic salt, 8-Hydroxyquinolinium 3,5-Dinitrobenzoate (8-HQH-3,5-DNB) was prepared by the simple protonation reaction of 8-Hydroxyquinoline (8-HQ) with 3,5-Dinitrobenzoic acid (DNBA). The formation of the organic salt 8-HQH-3,5-DNB was successfully confirmed by CHN elemental analysis, FT-IR and...

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Bibliographic Details
Published in:Chemical Data Collections 2021-06, Vol.33, p.100726, Article 100726
Main Authors: Satheesh, Dhurairaj, Roshini, Ragunathan, Jeevitha, Sekar, Chithra, Kasi, Vasanth Kumar, Srinivasan, Sellam, Periyasamy
Format: Article
Language:English
Subjects:
8-Hydroxyquinolinium 3,5-Dinitrobenzoate
Anti-diabetic activity
Anti-inflammatory activity
Ionic liquids
Organic material
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Summary:An organic salt, 8-Hydroxyquinolinium 3,5-Dinitrobenzoate (8-HQH-3,5-DNB) was prepared by the simple protonation reaction of 8-Hydroxyquinoline (8-HQ) with 3,5-Dinitrobenzoic acid (DNBA). The formation of the organic salt 8-HQH-3,5-DNB was successfully confirmed by CHN elemental analysis, FT-IR and 1H NMR spectral studies. The organic salt 8-HQH-3,5-DNB was screened to its anti-inflammatory and anti-diabetic activity in different concentrations (10, 25, 50, 125 and 250 μg/mL). The 8-HQH-3,5-DNB is showing very good anti-inflammatory and anti-diabetic activities compared to the corresponding standard drug.
ISSN:2405-8300
2405-8300
DOI:10.1016/j.cdc.2021.100726