Anti-inflammatory and anti-diabetic activity of 8-Hydroxyquinolinium 3,5-Dinitrobenzoate

An organic salt, 8-Hydroxyquinolinium 3,5-Dinitrobenzoate (8-HQH-3,5-DNB) was prepared by the simple protonation reaction of 8-Hydroxyquinoline (8-HQ) with 3,5-Dinitrobenzoic acid (DNBA). The formation of the organic salt 8-HQH-3,5-DNB was successfully confirmed by CHN elemental analysis, FT-IR and...

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Published in:Chemical Data Collections 2021-06, Vol.33, p.100726, Article 100726
Main Authors: Satheesh, Dhurairaj, Roshini, Ragunathan, Jeevitha, Sekar, Chithra, Kasi, Vasanth Kumar, Srinivasan, Sellam, Periyasamy
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Language:English
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8-Hydroxyquinolinium 3,5-Dinitrobenzoate
Anti-diabetic activity
Anti-inflammatory activity
Ionic liquids
Organic material
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Roshini, Ragunathan
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Sellam, Periyasamy
description An organic salt, 8-Hydroxyquinolinium 3,5-Dinitrobenzoate (8-HQH-3,5-DNB) was prepared by the simple protonation reaction of 8-Hydroxyquinoline (8-HQ) with 3,5-Dinitrobenzoic acid (DNBA). The formation of the organic salt 8-HQH-3,5-DNB was successfully confirmed by CHN elemental analysis, FT-IR and 1H NMR spectral studies. The organic salt 8-HQH-3,5-DNB was screened to its anti-inflammatory and anti-diabetic activity in different concentrations (10, 25, 50, 125 and 250 μg/mL). The 8-HQH-3,5-DNB is showing very good anti-inflammatory and anti-diabetic activities compared to the corresponding standard drug.
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subjects 8-Hydroxyquinolinium 3,5-Dinitrobenzoate
Anti-diabetic activity
Anti-inflammatory activity
Ionic liquids
Organic material
title Anti-inflammatory and anti-diabetic activity of 8-Hydroxyquinolinium 3,5-Dinitrobenzoate
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