Three-dimensional fully interconnected highly porous hydroxyapatite scaffolds derived from particle-stabilized emulsions

Three-dimensional (3D) macroporous hydroxyapatite (HAp) ceramics were fabricated via a facile emulsion templating technique for bone tissue engineering applications. The prepared scaffolds have an open, uniform, and 3D fully interconnected pore structure with high porosities, mechanical strength, an...

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Bibliographic Details
Published in:Ceramics international 2016-03, Vol.42 (4), p.5455-5460
Main Authors: Wang, Xiang, Li, Jin-hong, Xie, Ying-mei, Zhang, Hong-yao
Format: Article
Language:English
Subjects:
A. Suspensions
B. Porosity
D. Apatite
E. Biomedical applications
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Summary:Three-dimensional (3D) macroporous hydroxyapatite (HAp) ceramics were fabricated via a facile emulsion templating technique for bone tissue engineering applications. The prepared scaffolds have an open, uniform, and 3D fully interconnected pore structure with high porosities, mechanical strength, and a large surface/volume ratio. The porous structure, which is composed of an array of quasi-spherical large cells interconnected through windows, has a pore diameter in the range of 5–30μm. The samples sintered at the optimal temperature (1200°C) have an open porosity of ~76.5% and a high compressive strength of 4.26MPa. The technique discussed here is a significant advancement over other previously used methods to produce HAp ceramics and is expected to enable much improvement in the topology of the porous structure of scaffolds.
ISSN:0272-8842
1873-3956
DOI:10.1016/j.ceramint.2015.12.088