Simultaneous determination of bioactive flavone derivatives in Chinese herb extraction by capillary electrophoresis used different electrolyte systems—Borate and ionic liquids

In this paper, novel capillary electrophoresis (CE) methods, which used ionic liquids (1-ethyl-3-methylimidazoium tetrafluoroborate, 1-butyl-3-methylimidazoium tetrafluoroborate), were established to separate and determine some bioactive flavone derivatives in Chinese herb Seriphidium santolinum (Sc...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Chromatography A 2006-03, Vol.1109 (2), p.300-306
Main Authors: Qi, Shengda, Li, Yuqin, Deng, Yanru, Cheng, Yuqiao, Chen, Xingguo, Hu, Zhide
Format: Article
Language:English
Subjects:
Asteraceae - chemistry
beta-Cyclodextrins
Biological and medical sciences
Borates - chemistry
Capillary electrophoresis
Electrolytes - chemistry
Electrophoresis, Capillary - methods
Flavone derivatives
Flavones - analysis
General pharmacology
Ionic liquids
Ions
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
β-Cyclodextrin
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this paper, novel capillary electrophoresis (CE) methods, which used ionic liquids (1-ethyl-3-methylimidazoium tetrafluoroborate, 1-butyl-3-methylimidazoium tetrafluoroborate), were established to separate and determine some bioactive flavone derivatives in Chinese herb Seriphidium santolinum (Schrenk) Poljak. In order to investigate the traits of ionic liquids in CE, borate was also used as electrolyte to compare with. And the excellence of CE, which used ionic liquids as main running electrolyte and β-cyclodextrin (β-CD) as modifier, was illuminated as well. As a result of the study, the difference of ionic liquids and borate in CE was discussed and the advantage of CE, which used ionic liquids as electrolytes for separation, was shown. The analysis was obtained within short time (5–6 min). From the result, it was found that the system, which used ionic liquids, was robust because the joule heating was small. The method of CE, which used ionic liquids, has lower detection limits (0.137–0.642 μg/mL) than that of borate (0.762–1.036 μg/mL). And the CE, which used ionic liquids method, has lower limit of linear range (1.100–2.656 μg/mL), while that of CE, which used borate method, was 2.188–5.313 μg/mL.
ISSN:0021-9673
DOI:10.1016/j.chroma.2006.01.045