C Reactive Protein as a Predictor of Anastomotic Leakage in Colorectal Surgery. Comparison Between Open and Laparoscopic Surgery

Anastomotic leak (AL) is a serious complication in colorectal surgery due to its increase in morbidity and mortality. The aim of this prospective non-randomised study is to determine whether C-reactive Protein (CRP) is useful as a predictor of AL in patients undergoing open versus laparoscopic surge...

Full description

Saved in:
Bibliographic Details
Published in:Cirugia española (English ed.) 2017-11, Vol.95 (9), p.529-535
Main Authors: Ramos Fernández, María, Rivas Ruiz, Francisco, Fernández López, Alberto, Loinaz Segurola, Carmelo, Fernández Cebrián, José María, de la Portilla de Juan, Fernando
Format: Article
Language:English
Subjects:
Anastomotic leak
C reactive protein
Cirugía colorrectal
Colorectal surgery
Diagnostic test
Fuga anatomótica
Proteína C reactiva
Test diagnóstico
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Anastomotic leak (AL) is a serious complication in colorectal surgery due to its increase in morbidity and mortality. The aim of this prospective non-randomised study is to determine whether C-reactive Protein (CRP) is useful as a predictor of AL in patients undergoing open versus laparoscopic surgery. A total of 168 patients undergoing elective colorectal surgery were included. CRP was measured daily during the first 5 postoperative days. Complications, specially AL, were analyzed. Following an open approach 32 patients (45.7%) presented complications, 15 (18.7%) in the laparoscopic group and 12 (29.4%) in the converted group (P=0.153). Following open surgery 9 patients experienced AL, 5 were detected in the laparoscopic group and none in those converted (P=0.153). There were significant differences in CRP values between the 3 groups (P=0.03). ROC Curves showed AUC for the open and laparoscopic approach of 0.731 and 0.760 respectively. On day 4 the AUC was 0.867 for the open group and 0.914 for the laparoscopic group. Cut-off points on day 4 were: Open: 159.2mg/L; sensitivity 75%, specificity 89% and NPP 96% (P
ISSN:2173-5077
2173-5077
DOI:10.1016/j.cireng.2017.08.001