Modified Simultaneous Integrated Boost Radiotherapy for Unresectable Locally Advanced Breast Cancer: Preliminary Results of a Prospective Clinical Trial

Micro-Abstract Unresectable massive T4 breast tumor cannot be controlled by radiotherapy of ≤70Gy. Modified SIB irradiation technique enables to irradiate ≥100Gy to the tumor, keeping dose to the surrounding healthy tissue within tolerance dose. Huge tumors of all 3 patients enrolled in the clinical...

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Bibliographic Details
Published in:Clinical breast cancer 2015-04, Vol.15 (2), p.161-167
Main Authors: Nomiya, Takuma, Akamatsu, Hiroko, Harada, Mayumi, Ota, Ibuki, Hagiwara, Yasuhito, Ichikawa, Mayumi, Miwa, Misako, Suzuki, Akihiko, Nemoto, Kenji
Format: Article
Language:English
Subjects:
Adenocarcinoma - radiotherapy
Breast neoplasm
Breast Neoplasms - radiotherapy
Clinical trial
Female
Hematology, Oncology and Palliative Medicine
Humans
Middle Aged
Obstetrics and Gynecology
Radiotherapy
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted - methods
Radiotherapy, Intensity-Modulated - methods
Technique
Unresectable tumor
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Summary:Micro-Abstract Unresectable massive T4 breast tumor cannot be controlled by radiotherapy of ≤70Gy. Modified SIB irradiation technique enables to irradiate ≥100Gy to the tumor, keeping dose to the surrounding healthy tissue within tolerance dose. Huge tumors of all 3 patients enrolled in the clinical trial macroscopically disappeared by modified SIB radiotherapy.
ISSN:1526-8209
1938-0666
DOI:10.1016/j.clbc.2014.09.011