Bio-activation and mathematical modeling of ZIF-L encapsulated with laccase for enhanced ibuprofen removal from wastewater

• Published in: Cleaner Engineering and Technology 2025-02, Vol.24, p.100875, Article 100875
• Main Authors: Hassan, Ayat, Hasan, Shadi W., Van der Bruggen, Bart, Al-Zuhair, Sulaiman
• Format: Article
• Language: English
• Subjects: Adsorption breakthrough; Enzymes; Metal-organic frameworks (MOFs); Modeling; Nanomaterials; Pharmaceutical pollutants; Wastewaters
• ISSN: 2666-7908; 2666-7908
• DOI: 10.1016/j.clet.2024.100875

This work explores the bio-activation of zeolitic imidazolate framework (ZIF-L) by laccase encapsulation for enhanced performance of emerging pollutant removal from wastewater. ZIF-L exhibits high surface area, porosity, and selective adsorption characteristics, which contribute to its effective adsorption of ibuprofen. Under the same conditions, the ibuprofen removal increased from 50% using bare ZIF-L to 83% using bio-activated ZIF-L. The Kinetics and thermodynamics of ibuprofen adsorption on ZIF-L were studied and mathematically modeled. The effect of laccase encapsulation inside the ZIF-L crystals was thoroughly investigated using a diffusion-reaction model, which was solved numerically using a finite difference explicit scheme. The results showed deep ibuprofen penetration within the ZIF-L crystal containing encapsulated laccase. The bio-activated ZIF-L was used in a fixed-bed column to study the continuous removal of ibuprofen. The dynamic behavior of the continuous fixed-bed system was mathematically modeled to predict the concentration profiles and breakthrough curves at various initial ibuprofen concentrations. This study presents a novel approach demonstrating the positive effect of laccase catalytic activity in enhancing the performance of ZIF-L as an adsorbent for ibuprofen removal. The approach offers an effective, economical, and environmentally friendly method to remove emerging pollutants from wastewater. [Display omitted] •Utilizing ZIF- bio-activated with laccase is effective biocatalysis for ibuprofen removal.•Ibuprofen removal rate was significantly higher using the bioactive ZIF-L as compared to ZIF-L alone.•Diffusion-reaction kinetics model was used to describe the process.•Continuous ibuprofen removal was achieved using a fixed-bed column packed with bioactive ZIF-L.