ID 392 – Subclinic reinnervation in periocular muscles: High jitter values in diabetic polyneuropathy

• Published in: Clinical neurophysiology 2016-03, Vol.127 (3), p.e109-e109
• Main Authors: Baysal Kirac, L, Kocasoy Orhan, E, Baslo, M.B
• Format: Article
• Language: English
• Subjects: Neurology
• ISSN: 1388-2457; 1872-8952
• DOI: 10.1016/j.clinph.2015.11.367

Objective The aim of this study was to assess jitter abnormalities in periocular muscles of patients with diabetic polyneuropathy (DPN). Methods Twenty patients (9 F, 11 M; mean age 57.6 ± 10 years) who suffered from moderate and severe DPN were included in the study. Jitter values were assessed in 20 different pairs of voluntarily activated frontalis muscle using 25 mm concentric needle electrode with 1 kHz low-cut filtering. “Peak counts” were calculated as the number of electronegative peaks firing together with the triggering potential during jitter analysis in 20 different needle positions. Results For the frontalis muscle the mean jitter of all potential pairs was 30.9 ± 27.6 μs (8 −226 μs). The number of abnormal jitter values (⩾55 μs) were 40 out of 400 jitters (10%). Twenty-two of them were calculated from the traces harbouring 3 or more single-fiber like potentials which could be an indicator for reinnervation with collateral sprouting. Five out of 20 patients (25%) had more than two individual abnormal jitter values. The mean value of peak count was 2.4. Conclusions Increased jitter in frontalis muscle of patients with DPN is considered a function of reinnervation. Key message In diabetes frontalis muscle may exhibit jitter abnormalities.