Peripheral nerve disorders O-PN001. Comparison of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio before and after plasma exchange treatment in Guillain-barre syndrome patients

Introduction. Plasma exchange (PE) was the first treatment in Guillain-Barre ́Syndrome (GBS) proven to be superior to supportive treatment alone. Several studies have evaluated the PE efficacy for GBS. Recently, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are known to...

Full description

Saved in:
Bibliographic Details
Published in:Clinical neurophysiology 2021-08, Vol.132 (8), p.e75-e76
Main Authors: Juananda, Desby, Asmedi, Ahmad, Ghazali Malueka, Rusdy, Sari Kusuma Harahap, Indra
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction. Plasma exchange (PE) was the first treatment in Guillain-Barre ́Syndrome (GBS) proven to be superior to supportive treatment alone. Several studies have evaluated the PE efficacy for GBS. Recently, neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are known to be widely used as a biomarker of inflammation and a predictor of prognosis in various disorders. This study investigates whether the NLR and PLR were the laboratory parameters that associated with the treatment of GBS. Methods. Fifty-two adults with GBS were retrospectively analysed from the electronic medical records of patients who attended to the Neurology Department of Dr. Sardjito General Hospital, Yogyakarta, Indonesia from January 2016 to September 2019. The NLR and PLR before and after PE treatment in all patients were calculated and analysed with Wilcoxon signed-rank test (p 
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2021.02.154