Vitamin D levels and chronic hepatitis C

Summary Background and purpose Vitamin D (VitD) is involved in homeostasis of calcium and interacts with parathyroid hormone (PTH). Low levels of VitD in chronic liver diseases, in particular in chronic hepatitis C (CHC) was reported. We aimed to determine the levels of VitD and PTH in patients with...

Full description

Saved in:
Bibliographic Details
Published in:e-SPEN journal 2013-08, Vol.8 (4), p.e169-e174
Main Authors: Morisco, Filomena, Colao, Annamaria, Guarino, Maria, Lembo, Vincenzo, Granata, Rocco, Donnarumma, Laura, Auriemma, Francesco, Mariniello, Anna, Mazzone, Giovanna, Di Somma, Carolina, Rubino, Manila, Cariati, Federica, Pivonello, Claudia, Loperto, Ilaria, Caporaso, Nicola
Format: Article
Language:English
Subjects:
blood serum
Calcium
calcium phosphates
chemiluminescence immunoassays
Chronic hepatitis C
Gastroenterology and Hepatology
Health problem
homeostasis
Internal Medicine
Parathyroid hormone
patients
Phosphate
public health
vitamin D
Vitamin D deficiency
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Background and purpose Vitamin D (VitD) is involved in homeostasis of calcium and interacts with parathyroid hormone (PTH). Low levels of VitD in chronic liver diseases, in particular in chronic hepatitis C (CHC) was reported. We aimed to determine the levels of VitD and PTH in patients with CHC without cirrhosis to evaluate the disturbance of VitD-PTH axis. Methods We conduced a case–control study enrolling 59 patients with CHC and 59 controls. We determined serum concentration of VitD, PTH, calcium and phosphate. VitD was quantified by chemiluminescence immunoassay. PTH was measured by 2-site chemiluminescent enzyme-labeled immunoassay. Results The mean value of VitD was 26.28 and 28.43 ng/ml in HCV patients and controls respectively ( p  
ISSN:2212-8263
2212-8263
DOI:10.1016/j.clnme.2013.04.006