Chromosome Dynamics: Actin’s Gone Fishing

Chromosome congression and segregation have been widely known to be coordinated by the function of the dynamic spindle microtubules. But recent work suggests that oocytes may employ a unique actin-dependent mechanism of chromosome delivery to the spindle.

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Bibliographic Details
Published in:Current biology 2005-10, Vol.15 (20), p.R841-R842
Main Authors: Rizk, Rania S., Walczak, Claire E.
Format: Article
Language:English
Subjects:
Actins - metabolism
Actins - physiology
Animals
Bridged Bicyclo Compounds, Heterocyclic
Chromosome Segregation - physiology
Depsipeptides
Models, Biological
Nocodazole
Oocytes - physiology
Phalloidine
Spindle Apparatus - physiology
Starfish - physiology
Thiazoles
Thiazolidines
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Description
Summary:Chromosome congression and segregation have been widely known to be coordinated by the function of the dynamic spindle microtubules. But recent work suggests that oocytes may employ a unique actin-dependent mechanism of chromosome delivery to the spindle.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2005.10.004