Chloro-hydroxyl-merocyanine based turn-on fluorescent probes for the detection of hydrazine in water and living cells

Hydrazine (N2H4) is a very important chemical reagent which has been widely used in the fields of chemistry industry, aerospace, pesticide production and others. However, N2H4 is highly toxic and prone to induce a variety of diseases. Hence, we designed two fluorescent probes (CH–NO1, CH–NO2) based...

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Bibliographic Details
Published in:Dyes and pigments 2022-04, Vol.200, p.110109, Article 110109
Main Authors: Li, Kai-Bin, Chen, Yiyu, Zhou, Tianshuo, Wang, Tianlin, Wu, Dian, Pan, Yuanjiang, Zhang, Siqi, Shi, Wei, Wang, Feiyi, Ren, Jun
Format: Article
Language:English
Subjects:
Fluorescent probe
Hydrazine
Image analysis
Near infrared emission
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Summary:Hydrazine (N2H4) is a very important chemical reagent which has been widely used in the fields of chemistry industry, aerospace, pesticide production and others. However, N2H4 is highly toxic and prone to induce a variety of diseases. Hence, we designed two fluorescent probes (CH–NO1, CH–NO2) based on chloro-hydroxyl-merocyanine (CHMC) with similar recognition groups. The two probes were synthesized by a simple reaction coupling between CHMC dye and two alkyl bromine compounds. Both probes showed specific off-on response to N2H4 in aqueous solution with nanomolar LOD (28 nM for CH–NO1 and 38 nM for CH–NO2), and without interference by a range of amino acids, anions and cations. Moreover, CH–NO1 can be used for both environmental and biological monitoring of N2H4. •Specific off-on switching response to N2H4 with near infrared luminescence.•The probe showed nanomolar LOD for detecting N2H4.•Allowed to sense N2H4 in both environmental and biological monitoring.
ISSN:0143-7208
1873-3743
DOI:10.1016/j.dyepig.2022.110109