Effect of intrathecal meperidine and intravenous amino acid infusion in reducing intraoperative shivering during spinal anesthesia: A prospective randomized trial

This is a prospective randomized double blind study to compare the efficacy of intravenous amino acid infusion versus meperidine added to intrathecal hyperbaric bupivacaine in reducing intraoperative shivering in parturient undergoing elective cesarean section under spinal anesthesia. Sixty patients...

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Bibliographic Details
Published in:Egyptian journal of anaesthesia 2016-07, Vol.32 (3), p.391-396
Main Authors: Mahmoud, Mohamed Sidky, Kamal, Manal Mohamed, Abdellatif, Ayman M., Elfawal, Sanaa Mohamed
Format: Article
Language:English
Subjects:
Amino acids
Bupivacaine
Cesarean section
Meperidine
Shivering
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Summary:This is a prospective randomized double blind study to compare the efficacy of intravenous amino acid infusion versus meperidine added to intrathecal hyperbaric bupivacaine in reducing intraoperative shivering in parturient undergoing elective cesarean section under spinal anesthesia. Sixty patients were randomly allocated into two groups. Group (A) (Amino-acid) (n=30) who received 2ml of 0.5% hyperbaric bupivacaine and ½ml normal saline 0.9% (total volume 2.5ml) intrathecal with intravenous administration of amino acids (Aminoven 5%, Fresenius Kabi), infused at rate 3ml/kg/h with the start of spinal anesthesia and throughout the operation. Group (M) (meperidine) (n=30) who received 2ml of 0.5% hyperbaric bupivacaine with 10mg meperidine in ½ml volume (total volume 2.5ml) intrathecal with intravenous administration of normal saline 0.9% at 3ml/kg/h with the start of spinal anesthesia. Group (A) showed significantly higher core temperature from 20 to 60min than group (M) (p
ISSN:1110-1849
1687-1804
1110-1849
DOI:10.1016/j.egja.2016.04.005