Environmental risk factors for sporadic acoustic neuroma (Interphone Study Group, Germany)

Abstract The only known risk factor for sporadic acoustic neuroma is high-dose ionising radiation. Environmental exposures, such as radiofrequency electromagnetic fields and noise are under discussion, as well as an association with allergic diseases. We performed a population-based case-control stu...

Full description

Saved in:
Bibliographic Details
Published in:European journal of cancer (1990) 2007-07, Vol.43 (11), p.1741-1747
Main Authors: Schlehofer, B, Schlaefer, K, Blettner, M, Berg, G, Böhler, E, Hettinger, I, Kunna-Grass, K, Wahrendorf, J, Schüz, J
Format: Article
Language:English
Subjects:
Acoustic neuroma
Adult
Aged
Allergy
Biological and medical sciences
Brain tumour
Case-Control Studies
Case-control study
Cell Phone - statistics & numerical data
Electromagnetic fields
Electromagnetic Fields - adverse effects
Environmental Exposure - adverse effects
Epidemiology
Female
Germany - epidemiology
Hearing Disorders - epidemiology
Hematology, Oncology and Palliative Medicine
Humans
Ionising radiation
Male
Medical sciences
Middle Aged
Mobile phone
Neuroma, Acoustic - epidemiology
Noise
Noise, Occupational - adverse effects
Noise, Occupational - statistics & numerical data
Pharmacology. Drug treatments
Radiation, Ionizing
Risk Factors
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract The only known risk factor for sporadic acoustic neuroma is high-dose ionising radiation. Environmental exposures, such as radiofrequency electromagnetic fields and noise are under discussion, as well as an association with allergic diseases. We performed a population-based case-control study in Germany investigating these risk factors in 97 cases with acoustic neuroma, aged 30 to 69 years, and in 194 matched controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in multiple logistic regression models. Increased risks were found for exposure to persistent noise (OR = 2.31; 95% CI 1.15–4.66), and for hay fever (OR = 2.20; 95% CI 1.09–4.45), but not for ionising radiation (OR = 0.91; 95 % CI 0.51–1.61) or regular mobile phone use (OR = 0.67; 95% CI 0.38–1.19). The study confirms results of recently published studies, although the pathogenetic mechanisms are still unknown.
ISSN:0959-8049
1879-0852
DOI:10.1016/j.ejca.2007.05.008