Role of diffusion-weighted imaging with ADC mapping and in vivo 1H-MR spectroscopy in thyroid nodules

To evaluate the role of the combined techniques of apparent diffusion coefficient (ADC) generated from diffusion-weighted magnetic resonance (MR) imaging (DWI) and metabolite spectrum acquired by magnetic resonance spectroscopy (MRS) in differentiating benign from malignant thyroid nodules. Thirty-s...

Full description

Saved in:
Bibliographic Details
Published in:Egyptian journal of radiology and nuclear medicine 2012-06, Vol.43 (2), p.183-192
Main Authors: El-Hariri, Mona A., Gouhar, Ghada K., Said, Nagwa S., Riad, Mohamed M.
Format: Article
Language:English
Subjects:
ADC
MRS
Thyroid nodules
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate the role of the combined techniques of apparent diffusion coefficient (ADC) generated from diffusion-weighted magnetic resonance (MR) imaging (DWI) and metabolite spectrum acquired by magnetic resonance spectroscopy (MRS) in differentiating benign from malignant thyroid nodules. Thirty-seven patients with 56 thyroid nodules were evaluated with conventional MRI (T1- & T2-WI), DWI (b value 0.500s/mm2; ADC values were calculated for the thyroid nodules), and MRS (for the presence or absence of choline peak). The ADC values and MRS findings were correlated with the histopathological results. The mean ADC of the malignant thyroid nodules (0.89±0.27×10−3mm2/s) was significantly lower than that of the mean ADC of the benign thyroid nodules (1.85±0.24×10−3mm2/s) (p value
ISSN:0378-603X
DOI:10.1016/j.ejrnm.2012.01.007