Hydrogen MR spectroscopy of neck masses

The purpose of this study is to evaluate the role of MR spectroscopy in differentiation between benign and malignant neck masses. Thirty-two patients having neck masses underwent routine MRI of the neck as well as Hydrogen 1 (1H) MR spectroscopy with echo time of 270ms at 1.5T. Peak amplitudes of ch...

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Bibliographic Details
Published in:Egyptian journal of radiology and nuclear medicine 2012-09, Vol.43 (3), p.421-427
Main Authors: Fahmy, Dalia Monir, El-Hawarey, Galal, El-Serougy, Lamiaa, EL-Ashry, Mohamed Saad
Format: Article
Language:English
Subjects:
Benign
Malignant
Spectroscopy
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Summary:The purpose of this study is to evaluate the role of MR spectroscopy in differentiation between benign and malignant neck masses. Thirty-two patients having neck masses underwent routine MRI of the neck as well as Hydrogen 1 (1H) MR spectroscopy with echo time of 270ms at 1.5T. Peak amplitudes of choline (Cho) & creatine (Cr) for each lesion as well as normal appearing muscle of the neck were obtained. Results were compared by using a nonparametric t test. Thirty-two lesions were included (14 benign) & (18 malignant). Mean value (±standard deviation) was 4.42±0.83 for malignant tumors and 1.93±0.74 for benign tumors. Also spectra were obtained from normal appearing muscles with average Cho/Cr ratio 1.59±0.49. Differences were significant between benign & malignant tumors as well as between malignant tumors & normal appearing muscles (p value
ISSN:0378-603X
DOI:10.1016/j.ejrnm.2012.04.006