Industrial waste reuse: An alternative source to reduced graphene oxide for preparing electrochemical sensors

• Published in: Electrochimica acta 2023-06, Vol.454, p.142382, Article 142382
• Main Authors: Melo, Jaqueline F., Junior, Joadir H.S., Freire, Thais B.de M., Rigoti, Eduardo, Pergher, Sibele B.C., Martínez-Huitle, Carlos A., Castro, Pollyana S.
• Format: Article
• Language: English
• Subjects: Electrochemical sensor; Paracetamol determination; Real samples; Recycled-rGO; Reuse of industrial waste
• ISSN: 0013-4686; 1873-3859
• DOI: 10.1016/j.electacta.2023.142382

•Industrial waste was used as carbonaceous source for recycled reduced graphene oxide (r-rGO) synthesis.•A r-rGO modifier electrode material was applied in a glassy carbon electrode forming a sensitive sensor to monitoring drugs in tablets.•Electroanalysis of paracetamol in real tablet samples were carried out as a proof of concept and the results compared with HPLC official method. Development of sustainable electroanalytical platforms based on recovering approaches has great importance, once that they aim to minimize waste and increase reusing/recycling efforts, as well as engage the circular economy. This work converted an industrial waste carbon source to a recycled reduced graphene oxide (r-rGO) using a cost effective wide scale synthesis. The r-rGO was characterized by SEM, XRD, FTIR, and Raman spectroscopy techniques and as a proof-of-concept the new material was applied as electrode modifier for paracetamol (PAR) electroanalytical determination in tablets. The simple, easy and rapid technique of drop casting a suspension solution of r-rGO, was used to prepare the surface of a chemically modified glassy carbon electrode (GCE) forming a r-rGO/GCE sensor. Differential pulse voltammetry (DPV) was optimized and applied successfully in the paracetamol determination with a linear range of 60–500 μmol L−1 and detection limit of 0.28 μmol L−1. Then, two commercialy avaliable paracetamol tablets were used, with a minimum sample preparation, achieving recoveries of 99.43% and 100.47%. A HPLC (high performance liquid chromatography) comparative method was performed obtaining recoveries of 100.92% and 101.00%. Finally, the obtained results demonstrate that the r-rGO/GCE sensor can be a promising alternative for the quantitative determination of PAR in pharmaceutical formulations. [Display omitted]