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PCDD/F and PCB concentrations in sera from the Canadian Health Measures Survey (CHMS) from 2007 to 2009

In order to establish a national baseline estimate of the concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) in Canadians, pooling of individual human sera was performed to ensure that a high frequency of detectable concentrations of...

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Bibliographic Details
Published in:Environment international 2012-10, Vol.47, p.48-55
Main Authors: Rawn, Dorothea F.K., Ryan, J. Jake, Sadler, Amy R., Sun, Wing-Fung, Haines, Douglas, Macey, Kristin, Van Oostdam, Jay
Format: Article
Language:English
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Summary:In order to establish a national baseline estimate of the concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) in Canadians, pooling of individual human sera was performed to ensure that a high frequency of detectable concentrations of analytes would be achieved. Nearly 5000 (4583) sera samples from Cycle 1 of the Canadian Health Measures Survey (CHMS) collected between 2007 and 2009 were used to form 59 composite pools of approximately 25mL each. Pools were categorized by sex and age with participants ranging from 6 to 79years. The pooled samples were analysed for 17 PCDD/Fs and 36 PCB congeners, and from these data, total toxic equivalent concentrations (TEQ2005 PCDD/F+Dioxin-like [DL]-PCB) were estimated. The average 2,3,7,8 tetrachlorodibenzodioxin (TCDD) concentration was
ISSN:0160-4120
1873-6750
DOI:10.1016/j.envint.2012.05.008