Short-term molecular-level effects of silver nanoparticle exposure on the earthworm, Eisenia fetida

Short-term changes in levels of expression of nine stress response genes and oxidative damage of proteins were examined in Eisenia fetida exposed to polyvinylpyrrolidone (PVP) coated Ag nanoparticles (Ag-NP) and AgNO3 in natural soils. The responses varied significantly among days with the highest n...

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Bibliographic Details
Published in:Environmental pollution (1987) 2012-12, Vol.171, p.249-255
Main Authors: Tsyusko, Olga V., Hardas, Sarita S., Shoults-Wilson, W. Aaron, Starnes, Catherine P., Joice, Greg, Butterfield, D. Allan, Unrine, Jason M.
Format: Article
Language:English
Subjects:
acute toxicity
Animal, plant and microbial ecology
Animals
Annelida and closely related phyla: sipuncula. Echiura. Nemertinea
Applied ecology
Biological and medical sciences
Catalase
Catalase - genetics
Catalase - metabolism
earthworms
Ecotoxicology, biological effects of pollution
Eisenia fetida
Fundamental and applied biological sciences. Psychology
Gene expression
Gene Expression - drug effects
General aspects
genes
HSP70 Heat-Shock Proteins - genetics
HSP70 Heat-Shock Proteins - metabolism
Invertebrates
ions
Metal Nanoparticles - toxicity
nanoparticles
nanosilver
Oligochaeta
Oxidative damage
Oxidative Stress
Povidone - toxicity
proteins
silver
Silver - toxicity
Silver nanoparticles
Soil
Soil Pollutants - toxicity
stress response
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Summary:Short-term changes in levels of expression of nine stress response genes and oxidative damage of proteins were examined in Eisenia fetida exposed to polyvinylpyrrolidone (PVP) coated Ag nanoparticles (Ag-NP) and AgNO3 in natural soils. The responses varied significantly among days with the highest number of significant changes occurring on day three. Similarity in gene expression patterns between Ag-NPs and AgNO3 and significant relationships of expression of CAT and HSP70 with Ag soil concentration suggest similarity in toxicity mechanisms of Ag ions and NPs. Significant increases in the levels of protein carbonyls on day three of the exposure to both ions and Ag-NPs indicate that both treatments induced oxidative stress. Our results suggest that Ag ions drive short term toxicity of Ag-NPs in E. fetida. However, given that
ISSN:0269-7491
1873-6424
DOI:10.1016/j.envpol.2012.08.003