Lead seasonality in humans, animals, and the natural environment

• Published in: Environmental research 2020-01, Vol.180, p.108797, Article 108797
• Main Authors: Levin, Ronnie, Zilli Vieira, Carolina L., Mordarski, Daniel C., Rosenbaum, Marieke H.
• Format: Article
• Language: English
• Subjects: Av gas; Hunting seasons; Lead exposure; Lead seasonality; One health
• ISSN: 0013-9351; 1096-0953
• DOI: 10.1016/j.envres.2019.108797

Lead adversely impacts the health of humans, animals, and the natural environment. Higher lead burdens in warm weather occur in humans, domesticated and wild animals; land and water species; urban and rural, developed and pristine environments. The array of evidence suggests that lead seasonality is multifactorial within the natural world, including humans. Seasonally higher temperatures, solar radiation, humidity and anthropogenic pollution result in lower pH (acidification) in air, water and soil. Environmental acidification increases lead's bioavailability and mobility thus intensifying human, animal and plant exposures. In addition, lead seasonality in the biosphere is influenced by higher growth rates, slightly increased exposures, and more Vitamin D metabolism. Methodologically, we applied a One Health perspective to EPA's Integrated Science Assessments of Lead to review the published literature, supplemented with subsequent and related publications to assess data on the seasonality of lead exposure across species and through the earth's systems. Our integrated assessment suggests that: 1) ‘Seasonality’ is a multifactorial, terrestrial phenomenon affecting the natural world; human activities have exacerbated natural cyclicities that impact lead exposures across species. 2) To be sustainable, human lead remediation strategies must consider the total environment. 3) Global warming and climate change events may increase lead exposures and toxicity to all species throughout the natural environment. [Display omitted] Seasonality is predictive of Pb concentrations in humans, especially children.Lead seasonality is also evident across species throughout the natural world.Seasonal environmental acidification increases lead's bioavailability and mobility.Global warming will likely exacerbate Pb mobility and toxicity.