Hepatic abscess following NSAID use in an adolescent

Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) are a known cause of peptic ulcer disease, resulting in gastrointestinal bleeding or perforation. We present a case of a sixteen year old male athlete who presented with abdominal pain and was found to have a pyogenic liver abscess secondary to...

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Bibliographic Details
Published in:Journal of pediatric surgery case reports 2014, Vol.2 (1), p.33-36
Main Authors: Clark, Margaret E, Osten, Andrew W, Abbas, Mazen I, Edwards, Mary J
Format: Article
Language:English
Subjects:
Adolescent
Gastrohepatic fistula
NSAID
Peptic ulcer
Surgery
Ulcer perforation
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Summary:Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) are a known cause of peptic ulcer disease, resulting in gastrointestinal bleeding or perforation. We present a case of a sixteen year old male athlete who presented with abdominal pain and was found to have a pyogenic liver abscess secondary to a gastrohepatic fistula due to a deeply penetrating ulcer from NSAID use. This patient was successfully managed with antibiotics, a proton pump inhibitor (PPI), percutaneous drainage, and bowel rest. Perforating peptic ulcer disease (PPU) is rare in children, and this is a novel report of a resulting gastrohepatic fistula and subcapsular hepatic abscess. In otherwise healthy adolescents with abdominal complaints, a careful history of NSAID use should be obtained.
ISSN:2213-5766
2213-5766
DOI:10.1016/j.epsc.2013.12.006