Association of CYP1A1 gene polymorphism with chronic kidney disease: A case control study

Highlights • First report on significant association of CYP1A1 polymorphism with idiopathic CKD. • Association of CYP1A1*2A and *2C hetero-/homozygous genotype combination with CKD. • First report of its kind on Indian population.

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Bibliographic Details
Published in:Environmental toxicology and pharmacology 2013-07, Vol.36 (1), p.164-170
Main Authors: Siddarth, Manushi, Datta, Sudip K, Ahmed, Rafat S, Banerjee, Basu D, Kalra, Om P, Tripathi, Ashok K
Format: Article
Language:English
Subjects:
Adult
Case-Control Studies
Chronic kidney disease
CYP1A1
Cytochrome P-450 CYP1A1 - genetics
Emergency
Female
Gene polymorphism
Genetic Predisposition to Disease
Genotype
Humans
India - epidemiology
Male
Middle Aged
Polymorphism, Genetic
Renal Insufficiency, Chronic - genetics
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Description
Summary:Highlights • First report on significant association of CYP1A1 polymorphism with idiopathic CKD. • Association of CYP1A1*2A and *2C hetero-/homozygous genotype combination with CKD. • First report of its kind on Indian population.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2013.03.008