Health-Related Quality of Life and Associated Factors in Patients Undergoing Kidney Replacement Therapies

• Published in: Farmacia hospitalaria 2024-09
• Main Authors: Pereira-Céspedes, Alfonso, Jiménez-Morales, Alberto, Polo-Moyano, Aurora, Spruce-Esparza, Elizabeth, Palomares-Bayo, Magdalena, Martínez-Martínez, Fernando, Calleja-Hernández, Miguel Ángel
• Format: Article
• Language: English
• Subjects: calidad de vida; end-stage kidney disease; enfermedad renal estadio 5; kidney replacement therapy; quality of life; tratamiento renal sustitutivo
• ISSN: 1130-6343
• DOI: 10.1016/j.farma.2024.08.008

Characterize the health-related quality of life among patients undergoing kidney replacement therapy and to explore associated factors. A descriptive observational study was conducted using the Kidney Disease Quality of Life Short Form questionnaire to assess health-related quality of life. The Dader Method was employed to evaluate negative outcomes associated with medications. Face-to-face interviews and clinical records were utilized to collect sociodemographic and clinical data from patients undergoing kidney replacement therapy at the Nephrology Department of Virgen de las Nieves University Hospital (Granada, Spain). We explored the association between independent variables (clinical and demographic factors) and dependent variables (Mental Component Score and Physical Component Score) using the linear regression method. Ninety-one participants were included, 47 (48.35%) were females. The mean age was 62 years, 52 patients (57.14%) were on hemodialysis, 13 patients (14.29%) on peritoneal dialysis, and 26 patients (28.57%) on other forms of kidney replacement therapy. The study revealed a mean Physical Component Score of 40.89 and a Mental Component Score of 47.19. Additionally, 98.90% of the patients experienced negative outcomes associated with medications. Influential factors include age, comorbid conditions, the number of medications, and clinical parameters such as vitamin D and calcium levels. This study underscores significant findings in patients undergoing kidney replacement therapy, indicating low Mental Component Score and Physical Component Score, accompanied by negative outcomes associated with medications. Caracterizar la calidad de vida relacionada con la salud en tratamiento renal sustitutivo y explorar los factores asociados. Se llevó a cabo un estudio observacional descriptivo utilizando el cuestionario Kidney Disease Quality of Life Short Form para evaluar la calidad de vida relacionada con la salud. Se empleó el Método Dáder para evaluar los resultados negativos asociados con la medicación. Se realizaron entrevistas y se utilizaron historias clínicas para recopilar datos sociodemográficos y clínicos de pacientes sometidos a terapia de reemplazo renal en el servicio de nefrología del Hospital Universitario Virgen de las Nieves (Granada, España). Se exploró la asociación entre las variables independientes (factores clínicos y demográficos) y las variables dependientes (Puntuación del Componente Mental y Puntuación del Componente Físico)