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Novel ACE inhibitory peptides from enzymatic hydrolysate of Channa punctata protein: In vitro and In silico assay of structure-activity relationship

Channa punctata flesh meat is well known for its ethnomedicinal values. The objective of this study was to isolate and identify peptides having Angiotensin-Converting Enzyme (ACE) inhibitory potential from the Channa punctata fish protein hydrolysates (FPH) and to investigate the inhibitory mechanis...

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Bibliographic Details
Published in:Food bioscience 2024-10, Vol.61, p.104765, Article 104765
Main Authors: Das, Madhushrita, Gangopadhyay, Aditi, Saha, Achintya, Dhar, Pubali
Format: Article
Language:English
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Summary:Channa punctata flesh meat is well known for its ethnomedicinal values. The objective of this study was to isolate and identify peptides having Angiotensin-Converting Enzyme (ACE) inhibitory potential from the Channa punctata fish protein hydrolysates (FPH) and to investigate the inhibitory mechanism by docking study. ACE inhibitory potential of the ultrafiltrate of C. punctata 240 min protein hydrolysates was analysed. The PrAHyd240 (
ISSN:2212-4292
DOI:10.1016/j.fbio.2024.104765