Is IS ABA- 1 customized for Acinetobacter?

An insertion sequence (IS ABA- 1 ) was identified in Acinetobacter spp., but not in Enterobacteriacea and Pseudomonas aeruginosa. Numerous copies of the IS were identified in Acinetobacter strains containing the element. In one of the Acinetobacter baumannii strains, IS ABA- 1 was identified adjacen...

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Bibliographic Details
Published in:FEMS microbiology letters 2005-02, Vol.243 (2), p.425-429
Main Authors: Segal, Heidi, Garny, Seike, Elisha, B. Gay
Format: Article
Language:English
Subjects:
Acinetobacter
Promoters
Sulphonamide resistance
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Description
Summary:An insertion sequence (IS ABA- 1 ) was identified in Acinetobacter spp., but not in Enterobacteriacea and Pseudomonas aeruginosa. Numerous copies of the IS were identified in Acinetobacter strains containing the element. In one of the Acinetobacter baumannii strains, IS ABA- 1 was identified adjacent to sulII and transcription of the resistance gene is presumed to be dependent on promoter sequences within the IS. Since the IS is adjacent to ampC and bla OXA in this A. baumannii strain, it may be that IS ABA- 1 plays an important role in the expression of antibiotic resistance genes in this genus.
ISSN:0378-1097
1574-6968
DOI:10.1016/j.femsle.2005.01.005