New amide alkaloid from the aerial part of Piper capense L.f. (Piperaceae)

Together with apigenine dimethylether and piperchabamide A, a new amide alkaloid, Kaousine and the Z form of antiepilepsirine were isolated from the aerial part of Piper capense L.f (Piperaceae). Their structures were elucidated by spectrometric methods and their in vitro antiparasitic activities we...

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Bibliographic Details
Published in:Fitoterapia 2010-09, Vol.81 (6), p.632-635
Main Authors: Kaou, Ali Mohamed, Mahiou-Leddet, Valérie, Canlet, Cécile, Debrauwer, Laurent, Hutter, Sébastien, Azas, Nadine, Ollivier, Evelyne
Format: Article
Language:English
Subjects:
Amide alkaloid
Antiplasmodial activity
Comoro
Piper capense
Piperaceae
Plasmodium falciparum
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Summary:Together with apigenine dimethylether and piperchabamide A, a new amide alkaloid, Kaousine and the Z form of antiepilepsirine were isolated from the aerial part of Piper capense L.f (Piperaceae). Their structures were elucidated by spectrometric methods and their in vitro antiparasitic activities were evaluated on Plasmodium falciparum. A new amide alkaloid, Kaousine 1 was isolated from the aerial part of Piper capense together with Z-antiepilepsirine and known compounds. Their in vitro antiplasmodial activities were evaluated. [Display omitted]
ISSN:0367-326X
DOI:10.1016/j.fitote.2010.03.006