A new abietane diterpene from Glyptostrobus pensilis

A new abietane diterpene, glypensin A ( 1) and four known compounds, 12-acetoxy- ent-labda-8(17), 13 E-dien-15-oic acid ( 2), quercetin 3- O- α- L-arabinofuranoside ( 3), quercetin 3- O- β- D-galactopyranoside ( 4), β-sitosterol ( 5) were isolated from the branches and leaves of Glyptostrobus pensil...

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Bibliographic Details
Published in:Fitoterapia 2010-12, Vol.81 (8), p.1202-1204
Main Authors: Zhang, Yu-Mei, Yin, Run-Ting, Jia, Rui-Rui, Yang, En-Hu, Xu, Han-Mei, Tan, Ning-Hua
Format: Article
Language:English
Subjects:
Abietane diterpene
Glypensin A
Glyptostrobus pensilis
Taxodiaceae
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Summary:A new abietane diterpene, glypensin A ( 1) and four known compounds, 12-acetoxy- ent-labda-8(17), 13 E-dien-15-oic acid ( 2), quercetin 3- O- α- L-arabinofuranoside ( 3), quercetin 3- O- β- D-galactopyranoside ( 4), β-sitosterol ( 5) were isolated from the branches and leaves of Glyptostrobus pensilis (Staut.) Koch. Their structures were determined by MS, 1D- and 2D-NMR means. Compound 1 showed cytotoxicity on human chronic myeloid leukemia cell line K562 (IC 50 = 21.2 μM). A new abietane diterpene, glypensin A ( 1) and other four known compounds were isolated from the branches and leaves of Glyptostrobus pensilis. Compound 1 showed cytotoxicity on K562 (IC 50 = 21.2 μM). [Display omitted]
ISSN:0367-326X
DOI:10.1016/j.fitote.2010.08.001