Phenolic glycosides from Curculigo orchioides Gaertn

Five new chlorophenolic glucosides, curculigine E (1), curculigine F (2), curculigine G (3), curculigine H (5), curculigine I (6) and one new phenolic glycoside, orcinoside H (4), together with eight known phenolic glycosides (7–14) were isolated from the Curculigo orchioides Gaertn. Their structure...

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Bibliographic Details
Published in:Fitoterapia 2013-04, Vol.86, p.64-69
Main Authors: Wang, Zhen-Hui, Huang, Jian, Ma, Xiao-Ci, Li, Guo-Yu, Ma, Yue-Ping, Li, Ning, Wang, Jin-Hui
Format: Article
Language:English
Subjects:
Antiosteoporotic activity
Curculigo orchioides
Curculigo orchioides Gaertn
glucosides
NMR
nuclear magnetic resonance spectroscopy
Phenolic glycosides
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Summary:Five new chlorophenolic glucosides, curculigine E (1), curculigine F (2), curculigine G (3), curculigine H (5), curculigine I (6) and one new phenolic glycoside, orcinoside H (4), together with eight known phenolic glycosides (7–14) were isolated from the Curculigo orchioides Gaertn. Their structures were established by spectroscopic techniques (IR, UV, MS, 1D and 2D NMR). The isolated phenolic glycosides were evaluated for antiosteoporotic activity against MC3T3-E1 cell line using MTT assays. Compounds 1, 2, 3, and 5 showed moderate antiosteoporotic activity with the proliferation rate of 10.1–14.1%. [Display omitted]
ISSN:0367-326X
DOI:10.1016/j.fitote.2013.01.008