Application of polydopamine fibers mat for simultaneous detection of multi-class drug residues in various animal-original foods

• Published in: Food control 2022-02, Vol.132, p.108523, Article 108523
• Main Authors: Liang, Sihui, Dai, Hairong, Wang, Chunmin, Zhang, Huayin, Li, Jian, Xu, Qian, Zhang, Qiuping
• Format: Article
• Language: English
• Subjects: Animal-original foods; Drug residues; Fibers mat; Solid-phase extraction
• ISSN: 0956-7135; 1873-7129
• DOI: 10.1016/j.foodcont.2021.108523

Polydopamine/polystyrene fibers mat (PDA-PS FsM) was prepared as a novel solid phase extraction (SPE) adsorbent for the simultaneous extraction of multi-class veterinary drug residues in animal-original foods. On this basis, a screening method for the determination of 18 veterinary drug residues in 8 classes by UPLC-MS/MS was established. PDA-PS FsM was confirmed to have good adsorption-desorption performance. By comparing the matrix effect before and after SPE, it was proved that PDA-PS FsM had significant matrix removal ability. The whole sample preparation process was less than 5 min, only 20 mg PDA-PS FsM and 2.5 mL of organic solvent were needed. The limits of detection of the target analytes ranged from 0.1 to 3.2 μg kg−1, and the recoveries ranged from 92.59% to 102.86%, with the intra-day and inter-day relative standard deviations of 2.11%–10.57%, revealing satisfactory accuracy and precision. Finally, the practicability of the method was evaluated. •A method for simultaneous detection of multi-class drug residues is developed.•PDA-PS FsM is firstly prepared and evaluated as a novel SPE absorbent.•PDA-PS FsM exhibites outstanding extraction performance and purification ability.•Only 20 mg absorbent, 2.5 mL organic solvent and 2 g sample are needed.•The practical application of the method is evaluated in plenty of food samples.