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Effects of exposure to multiple heavy metals on biochemical and histopathological alterations in common carp, Cyprinus carpio L

Heavy metals are frequently encountered as mixtures of essential and non-essential elements. Therefore, evaluation of their toxic effects individually does not offer a realistic estimate of their impact on biological processes. We studied effects of exposure to mixtures of essential and toxic metals...

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Bibliographic Details
Published in:Fish & shellfish immunology 2017-11, Vol.70, p.461-472
Main Authors: Rajeshkumar, Sivakumar, Liu, Yang, Ma, Junguo, Duan, Hong Ying, Li, Xiaoyu
Format: Article
Language:English
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Summary:Heavy metals are frequently encountered as mixtures of essential and non-essential elements. Therefore, evaluation of their toxic effects individually does not offer a realistic estimate of their impact on biological processes. We studied effects of exposure to mixtures of essential and toxic metals (Cr, Cd and Pb) on biochemical, immunotoxicity level and morphological characteristics of the various tissues of a biomarker freshwater fish common carp using environmentally relevant concentrations. Fish were exposed to metal mixture through tank water for 7, 15 and 30 days, under controlled laboratory conditions. Tissue accumulation of the metals was measured using Atomic Absorption Spectrophotometric techniques. Chromium, cadmium and lead accumulation in muscle, gills, liver, kidney and intestine, tissue of common carp exposed to mixture metals for 30 days increased significant compared with control group (p 
ISSN:1050-4648
1095-9947
DOI:10.1016/j.fsi.2017.08.013