Synovial fluid: An alternative source for forensic DNA

In human remains that have undergone decomposition, blood and other biological tissues are recognized as sources for forensic DNA identification, yet the success rate is influenced by the extent of decomposition to the subcellular structures and nucleic acids. Thus, synovial fluid may be considered...

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Bibliographic Details
Published in:Forensic science international. Genetics supplement series 2011-12, Vol.3 (1), p.e323-e324
Main Authors: Vongpaisarnsin, Kornkiat, Charito, Wisut, Boonlert, Achara, Tonsrisawat, Nat, Jongsakul, Teerachote
Format: Article
Language:English
Subjects:
Forensic DNA
Hydrolysis
Synovial fluid
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Summary:In human remains that have undergone decomposition, blood and other biological tissues are recognized as sources for forensic DNA identification, yet the success rate is influenced by the extent of decomposition to the subcellular structures and nucleic acids. Thus, synovial fluid may be considered as an alternative source for forensic DNA recovery, as compared to other decomposed tissues. In this study, 24 samples (12 synovial, 8 blood, and 4 muscle tissue samples) were obtained from 12 decomposed bodies. Our results show that synovial fluid is a suitable source for forensic DNA recovery compared to decomposed blood or muscle tissue. In addition, no mixture or contamination of DNA was detected in synovial sources. Further study is required to determine whether an additional pre-treatment of the synovial sample with hydrolysis can potentially recover more DNA.
ISSN:1875-1768
1875-175X
DOI:10.1016/j.fsigss.2011.09.024