Genetic analysis of g.7260–7291 region of ANKRD1 in Japanese population

A new dinucleotide repeat marker located on g.7260–7291 region of ankyrin repeat domain 1 (ANKRD1) was analyzed, in order to obtain genetic data for Japanese population. A total of 26 genotypes were detected in 248 individuals and these were considered to be controlled by 9 alleles composed by [TA]4...

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Bibliographic Details
Published in:Forensic science international. Genetics supplement series 2013, Vol.4 (1), p.e358-e359
Main Authors: Nakamura, Shigeki, Murakami, Chikako, Maeda, Kazuho, Irie, Wataru, Sasaki, Chizuko, Watanabe, Toshimasa, Ohishi, Momoko, Kurihara, Katsuyoshi
Format: Article
Language:English
Subjects:
Ankyrin repeat domain 1
Dinucleotide repeat marker
Genotyping
Japanese population
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Summary:A new dinucleotide repeat marker located on g.7260–7291 region of ankyrin repeat domain 1 (ANKRD1) was analyzed, in order to obtain genetic data for Japanese population. A total of 26 genotypes were detected in 248 individuals and these were considered to be controlled by 9 alleles composed by [TA]4CA[TA]2, [TA]10, [TA]12, [TA]13, [TA]14, [TA]15, [TA]12[TTTA]2, [TA]17 and [TA]18. These alleles were designated as 7a, 10, 12, 13, 14, 15, 16a, 17 and 18, and allele frequencies were calculated as 0.450, 0.026, 0.008, 0.252, 0.046, 0.010, 0.183, 0.014 and 0.010, respectively. The distribution of genotypes fitted the Hardy–Weinberg equilibrium. The power of discrimination, heterozygosity and polymorphism information contents were 0.863, 0.697 and 0.743, respectively. These results suggested that this new dinucleotide repeat marker was useful for individual identification in forensic caseworks.
ISSN:1875-1768
1875-175X
DOI:10.1016/j.fsigss.2013.10.182