Effect of peritoneal dialysis on antioxidant defense system and oxidative stress

In this study we investigated the effect of peritoneal dialysis (PD) on some antioxidant markers and lipid peroxidation. The levels of malondialdehyde (MDA), erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GPx), vitamins A, E, and C, and total antioxidant capacity (TAC) were determin...

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Bibliographic Details
Published in:Hong Kong journal of nephrology 2012-10, Vol.14 (2), p.33-37
Main Authors: Montazerifar, Farzaneh, Karajibani, Mansour, Sanadgol, Houshang, Hashemi, Mohammad
Format: Article
Language:English
Subjects:
Antioxidant defense system
Chronic ambulatory peritoneal dialysis
Oxidative stress
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Summary:In this study we investigated the effect of peritoneal dialysis (PD) on some antioxidant markers and lipid peroxidation. The levels of malondialdehyde (MDA), erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GPx), vitamins A, E, and C, and total antioxidant capacity (TAC) were determined in 23 chronic ambulatory PD patients and 34 healthy controls. The results showed MDA level in patients were not significantly different from those in controls. Erythrocyte SOD and GPX activities and vitamin C level were significantly decreased in the chronic ambulatory PD group (p 
ISSN:1561-5413
1876-4371
DOI:10.1016/j.hkjn.2012.09.004