Genetic study on 10 STR loci in the Romanian population

A population study on 10 tetrameric STR loci (D3S1358, VWA, D8S1179, D21S11, D18S51, D16S539, D2S1338, D19S433, THO1 and FGA) was performed on 104 unrelated individuals from Romania (Bucharest area), by mean of multiplex PCR (AmpFl STR SGM plus) and capillary electrophoresis. The allele frequencies...

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Bibliographic Details
Published in:International Congress series 2004-04, Vol.1261, p.169-172
Main Authors: Barbarii, Ligia Elena, Rolf, Burkhard, Calistru, Petre, Dermengiu, Dan
Format: Article
Language:English
Subjects:
Genetic polymorphisms
Romanian population
Short tandem repeats
Online Access:Get full text
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Summary:A population study on 10 tetrameric STR loci (D3S1358, VWA, D8S1179, D21S11, D18S51, D16S539, D2S1338, D19S433, THO1 and FGA) was performed on 104 unrelated individuals from Romania (Bucharest area), by mean of multiplex PCR (AmpFl STR SGM plus) and capillary electrophoresis. The allele frequencies and the usual forensic statistical parameters were defined. A brief comparison of the allele frequency distributions with other available data from European populations is presented. All the analyzed loci met Hardy–Weinberg equilibrium expectations. The high discrimination and exclusion power of the combined system showed the forensic efficiency of these 10 genetic markers. The study is considered to be very useful for paternal lineage testing and identification purposes in current forensic practice with Romanian individuals.
ISSN:0531-5131
1873-6157
DOI:10.1016/j.ics.2003.12.106