Socket Preservation Using Two Anorganic Bovine Bone Materials

• Published in: International dental journal 2024-10, Vol.74, p.S230-S230
• Main Authors: Madi, Marwa, Naief, Nasser S Al, Alagl, Adel S
• Format: Article
• Language: English
• ISSN: 0020-6539
• DOI: 10.1016/j.identj.2024.07.085

The aim of the present clinical study was to evaluate the dimensional changes and new bone formation in extraction sockets augmented with two anorganic bovine bone materials, NuOss and Bio-Oss. Following to institutional review board approval from Imam Abdulrahman Bin Faisal University and patients’ consent, 16 patients aged 23-45 years (6 males and 10 females) with planed posterior teeth extraction for future implant placement were enrolled in the study. Following atraumatic tooth extraction, twenty extraction sockets were randomly augmented using either NuOss or Bio-Oss and subsequently covered with collagen membrane. Bucco-lingual dimensions were measured using CBCT scans at baseline and after six months before implant placement. Bone core biopsies were obtained for histomorphologic examination and were decalcified briefly using EDTA to preserve capability immunohistochemistry staining. T-tests were applied to compare buccolingual widths pre- and post-treatment, within and across groups. After 6-months, CBCT scans revealed that Bio-Oss exhibited greater radio-opacity compared to Nu-Oss. Both groups displayed buccolingual width shrinkage after 6-months that was non-significant in both groups (p=0.06). Specimens from both groups showed lamellar cortical bone as well as trabeculae of osteoid with partial and optimum integration, evidence of maturation and residual fragments of grafted bone. However, Bio-Oss grafted cases exhibited more pronounced inflammation and osteoclastic activity, suggesting superior biocompatibility with NuOss. While both NuOss and Bio-Oss grafting materials yielded positive results, showing bone integration and maturation, the current study suggests more favorable biocompatible results when using NuOss grafting materials for socket preservation.