Overview of current technical adaptations to the electro-mechanical lung simulator xPULM for use as an alternative method to animal testing

When developing biomedical technical solutions, ethical aspects must always be considered. Many innovations therefore implement the 3R strategy (Refinement, Reduction, Replacement) by Russel & Burch so that animal suffering can be minimized and in the best case, the number of animal experiments...

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Bibliographic Details
Published in:IFAC-PapersOnLine 2024, Vol.58 (9), p.166-171
Main Authors: Drauschke, Andreas, Paštěka, Richard
Format: Article
Language:English
Subjects:
3R principle
active lung simulation
alternative to animal testings
Biomedical Systems
xPULM
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Summary:When developing biomedical technical solutions, ethical aspects must always be considered. Many innovations therefore implement the 3R strategy (Refinement, Reduction, Replacement) by Russel & Burch so that animal suffering can be minimized and in the best case, the number of animal experiments can be reduced. One strategy to replace animal testing is the development of electro-mechanical models. In the present work, adaptations of the electro-mechanical lung simulator xPULM™ to implement the 3R strategy are presented.
ISSN:2405-8963
2405-8963
DOI:10.1016/j.ifacol.2024.07.390