Gold laced bio-macromolecules for theranostic application

Gold nanostructures are promising entities for various biomedical applications, due to their promising physical and optical properties. They can be tailored in different sizes and shapes to play vital roles for photothermal therapy, Biosensing, in vivo X-ray/CT contrast etc. Many biomacromolecules h...

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Bibliographic Details
Published in:International journal of biological macromolecules 2018-04, Vol.110, p.39-53
Main Authors: Yadav, Pranjali, Singh, Surya Prakash, Rengan, Aravind Kumar, Shanavas, Asifkhan, Srivastava, Rohit
Format: Article
Language:English
Subjects:
Animals
Biopolymers
Biosensor
Diagnostics
Gold - therapeutic use
Humans
Hypothermia, Induced - methods
Imaging
Macromolecules
Metal nanoparticles
Metal Nanoparticles - therapeutic use
Phototherapy - methods
Photothermal
Theranostic Nanomedicine - methods
Therapy
Wound healing
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Summary:Gold nanostructures are promising entities for various biomedical applications, due to their promising physical and optical properties. They can be tailored in different sizes and shapes to play vital roles for photothermal therapy, Biosensing, in vivo X-ray/CT contrast etc. Many biomacromolecules have been used for chemical reduction of ionic gold into zero-valent metallic nanoparticles of specific shape/size followed by stabilizing them for long term utilization. This review will sum up a range of biomacromolecules including Alginate, Agarose, Starch, Carragenan, Cellulose, Chitin, Chitosan, Collagen, Cyclodextrins, Chondrotin Sulfate, Dextran Sulfate, Fucoidan, Gelatin, Guar Gum and Hyaluronic Acid, whose functionalities have been explored in combination with gold nanoparticles for various biomedical applications.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2017.10.124