Thiazolidinediones associated with recurrent pleural effusions post coronary artery bypass surgery

We report the case of a patient in which thiazolidinediones (TZDs) were associated with recurrent pleural effusions post coronary artery bypass surgery, in spite of a normal left ventricular function. The potential mechanisms are discussed, particularly in relation to the “vascular leak syndrome”. T...

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Bibliographic Details
Published in:International journal of cardiology 2006-01, Vol.106 (2), p.273-275
Main Authors: Abdallah, Mouhamad H., Khalil, Pierre Bou, Jamaleddine, Ghassan, Salti, Ibrahim, Dakik, Habib A.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Coronary Artery Bypass
Coronary artery bypass surgery
Coronary Disease - surgery
Coronary heart disease
Diabetes mellitus
Diabetes Mellitus - drug therapy
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Heart
Humans
Male
Medical sciences
Middle Aged
Pleural Effusion - chemically induced
Pleural Effusion - diagnostic imaging
Pleural effusions
Pneumology
Radiography
Recurrence
Respiratory system : syndromes and miscellaneous diseases
Thiazolidinediones
Thiazolidinediones - adverse effects
Thiazolidinediones - therapeutic use
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Summary:We report the case of a patient in which thiazolidinediones (TZDs) were associated with recurrent pleural effusions post coronary artery bypass surgery, in spite of a normal left ventricular function. The potential mechanisms are discussed, particularly in relation to the “vascular leak syndrome”. This finding has important implications for the management of diabetic patients who are referred for coronary artery bypass surgery and who are on TZDs for glycemic control.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2004.12.069