Aortic dissection complicating pregnancy following prophylactic aortic root replacement in a woman with Marfan syndrome

Abstract Prophylactic aortic root replacement is the main factor explaining the increase in median probability of survival in Marfan syndrome (MFS) patients. In women with MFS, earlier root replacement has been suggested as a strategy to facilitate safe pregnancy. However, in this case report a preg...

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Bibliographic Details
Published in:International journal of cardiology 2007-09, Vol.120 (3), p.427-430
Main Authors: McDermott, Colleen D, Sermer, Mathew, Siu, Samuel C, David, Tirone E, Colman, Jack M
Format: Article
Language:English
Subjects:
Adult
Aneurysm, Dissecting - etiology
Aortic Aneurysm - etiology
Aortic dissection
Aortic root replacement
Aortic Valve - surgery
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cardiovascular
Diseases of the aorta
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Fatal Outcome
Female
Fetal Death
Heart Valve Prosthesis
Humans
Marfan syndrome
Marfan Syndrome - complications
Marfan Syndrome - surgery
Medical sciences
Pregnancy
Pregnancy Complications, Cardiovascular - surgery
Pregnancy Trimester, Second
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
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Summary:Abstract Prophylactic aortic root replacement is the main factor explaining the increase in median probability of survival in Marfan syndrome (MFS) patients. In women with MFS, earlier root replacement has been suggested as a strategy to facilitate safe pregnancy. However, in this case report a pregnant patient with MFS who sustained a Type B aortic dissection in her second trimester, with fatal outcome, despite having had a prophylactic aortic root replacement five months prior to conception is described.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2006.09.023