Biomarkers in acute coronary syndrome

Abstract Background Biomarkers play an important role in the diagnosis and risk stratification of patients with ischemic heart disease. Currently, troponin continues as the reference biomarker in acute coronary syndromes. However, there are other biomarkers that have shown additional value in improv...

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Bibliographic Details
Published in:IJC metabolic & endocrine 2015-09, Vol.8, p.20-23
Main Authors: del Val Martin, David, Sanmartín Fernández, Marcelo, Zamorano Gómez, Jose Luís
Format: Article
Language:English
Subjects:
Acute coronary syndrome
Biomarkers
C-reactive protein
Copeptin
Cystatin-C
Endocrinology & Metabolism
GDF-15
High-sensitivity troponin
miRNA
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Summary:Abstract Background Biomarkers play an important role in the diagnosis and risk stratification of patients with ischemic heart disease. Currently, troponin continues as the reference biomarker in acute coronary syndromes. However, there are other biomarkers that have shown additional value in improving sensitivity and prognostic information. Several promising molecules are reviewed, some related to cardiomyocyte structure and others working as inflammatory and renal function markers. Conclusions Although many biomarkers have been shown useful in some studies, further prospective studies are needed to establish their accurate usefulness in routine clinical practice.
ISSN:2214-7624
2214-7624
DOI:10.1016/j.ijcme.2015.04.003